MétaCan
Menu
Back to cohort
Record W2104968730 · doi:10.5376/ijmms.2015.05.0002

Effect of <i>Polistes fuscatus</i> (Hymenoptera: wasp) Venom Extract on Phenobarbitone Sleeping Time in Albino Rats (<i>Rattus norvegicus</i>)

2015· article· en· W2104968730 on OpenAlexvenueno aff
Kayode David Ileke

Bibliographic record

VenueInternational Journal of Molecular Medical Science · 2015
Typearticle
Languageen
FieldNeuroscience
TopicNeurobiology and Insect Physiology Research
Canadian institutionsnot available
Fundersnot available
KeywordsHymenopteraVenomPaper waspPolistesBiologyToxicologyZoologyVespidaePharmacologyEcology

Abstract

fetched live from OpenAlex

Wasp of the cosmopolitan genus Polistes are the familiar of the Polistine wasps. The sting and venom have been evolved to be effective weapons against predators. The biological activities of the wasp venom have been classified as neurotoxin, haemolytic, and algogenic. This study monitors the effect of the wasp venom to potentiate the sleeping time in albino rats. Thirty (30) male albino rats with body weight of 120-170 g were used. The rats were divided into three groups (treatment, reference, and control), the treatment was further divided into three groups based on the dosage into mild, moderate and high dose, each group has six replicate. The treatment rats received 50 mg/kg, 100 mg/kg, and 200 mg/kg of the venom extract and were later given 40mg/kg phenobarbitone injection, thirty minutes after the administration of the venom extract, the reference group received 40mg/kg phenobarbitone injection and the control rats received 40 mg/kg of the extract. The result shows that increase in dosage is directly proportional to the sleeping response of the rats in the treatment group. The dosage (50 mg/kg, 100 mg/kg, and 200 mg/kg) induced a mean sleeping time of 306.16 minutes, 323.20 minutes and 373.17 minutes respectively. A significant increase ( p <0.05) in sleeping time was recorded in the rats that received high dose of the venom extract compared to other groups. The control rats recorded a mean sleeping time of 210 minutes, while the reference group recorded a mean sleeping time of 325 minutes. The sedative ability of the wasp venom has been demonstrated with this study, with sedation beginning within 20-30 minutes and reaching the peak at hours (post inoculation).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.003
Scholarly communication0.0000.001
Open science0.0040.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.314
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of Molecular Medical ScienceSame topicNeurobiology and Insect Physiology ResearchFrench-language works237,207