Efficacy of Modified Eggs and Chick Muscles on Oxidative Stress of Type-2 Diabetes Mellitus Induced Male Wistar Rats
Bibliographic record
Abstract
A modified poultry egg (Indian Patent Application No. 2264/Del-2005) and chick muscle enriched with optimum minerals, vitamin E and omega-3 fatty acid were developed and its efficacy was studied on oxidative stress of Type-2 diabetes mellitus induced male wistar rats. In this study, two groups of rats were fed on semi-synthetic diet containing 20 mg Zn/kg (control, group-I) and 80 mg Zn/kg (group-II) diet respectively for a period of 6 months. The study revealed that the gain in body weight increased in rats in Zn concentration dependent manner. The urine examined on weekly basis showed glucosuria in group-II on week 8 and thereafter. The blood lipid profile displayed a significant rise in serum glucose, total lipids, cholesterol, triglycerides, LDL-cholesterol, VLDL-cholesterol whereas HDL-cholesterol showed a reduction in their levels in group-II rats than their control counter parts. They displayed higher lipid peroxidation products and activities of superoxide dismutase, catalase, glutathione–s -transferase, glutathione reductase, glutathione (reduced) and glucose-6-phosphate dehydrogenase were significantly lowered and revealed a higher Zn concentration and lower Cu, Mg and Mn both in liver and kidney. On day 90, the male rats in group-II after the establishment of type-2 diabetes mellitus, were divided in to two groups- group-IIA and group-IIB. Feeding on these eggs and chick muscles mixed diet in these groups of rats, all the abnormalities were restored and a considerable reduction in lipid peroxidation products and a significant increased in the activities of enzymes per se with reversal of Zn, Cu, Mg and Mn levels closer to the control group were recorded. The present data suggest that these modified egg and chick muscle are effective in ameliorating the oxidative stress in type-2 diabetes mellitus induced male rats.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".