Frequency response of assemblies of biological cells exposed to electric fields
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Bibliographic record
Abstract
For most cell types, gap junctions connect the interiors of neighbouring cells and provide the local intercellular communication that is essential for normal biological cell processes. In this work, we test the hypothesis that the frequency responses of gap-connected cells exposed to electric fields differ from those of isolated cells. The frequency responses of geometrically complex models of gap-connected cell configurations are evaluated using the finite element method. Results indicate that the inclusion of gap junctions changes the frequency behaviour of the cells. A group of gap-connected cells can be modeled as a lowpass filter cascaded with a bandstop filter. The lowpass filter corresponds to the frequency behaviour of a single cell with the same shape as the configuration. The bandstop filter represents the gap junctions. The characteristics of the stopband of this filter depend in a complex way on the properties of the gap junctions, such as area, conductivity and location.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it