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Record W2106247158 · doi:10.1002/cjs.5550330407

Cure rate models: A unified approach

2005· article· en· W2106247158 on OpenAlexvenueno aff
Guosheng Yin, Joseph G. Ibrahim

Bibliographic record

VenueCanadian Journal of Statistics · 2005
Typearticle
Languageen
FieldMathematics
TopicStatistical Methods in Clinical Trials
Canadian institutionsnot available
Fundersnot available
KeywordsComputer scienceMarkov chain Monte CarloMarkov chainCovariateClass (philosophy)PopulationBayesian probabilityMathematicsArtificial intelligenceMachine learning

Abstract

fetched live from OpenAlex

The authors propose a novel class of cure rate models for right-censored failure time data. The class is formulated through a transformation on the unknown population survival function. It includes the mixture cure model and the promotion time cure model as two special cases. The authors propose a general form of the covariate structure which automatically satisfies an inherent parameter constraint and includes the corresponding binomial and exponential covariate structures in the two main formulations of cure models. The proposed class provides a natural link between the mixture and the promotion time cure models, and it offers a wide variety of new modelling structures as well. Within the Bayesian paradigm, a Markov chain Monte Carlo computational scheme is implemented for sampling from the full conditional distributions of the parameters. Model selection is based on the conditional predictive ordinate criterion. The use of the new class of models is illustrated with a set of real data involving a melanoma clinical trial.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.024
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.010
Threshold uncertainty score0.055

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.024
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0040.003
Science and technology studies0.0010.002
Scholarly communication0.0040.005
Open science0.0050.003
Research integrity0.0040.006
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.592
GPT teacher head0.481
Teacher spread0.111 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations170
Published2005
Admission routes1
Has abstractyes

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