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Record W2106362781 · doi:10.1517/14740338.3.1.25

The safety of antihypertensives for treatment of pregnancy hypertension

2004· review· en· W2106362781 on OpenAlexaff
Laura A. Magee, Sarimah Abdullah

Bibliographic record

VenueExpert Opinion on Drug Safety · 2004
Typereview
Languageen
FieldMedicine
TopicPregnancy and preeclampsia studies
Canadian institutionsB.C. Women's Hospital & Health Centre
Fundersnot available
KeywordsMedicinePregnancyObservational studyHypertension in PregnancyAntihypertensive drugAmbulatoryAmbulatory blood pressureDrugs in pregnancyBlood pressureIntensive care medicinePharmacotherapyDrugFetusObstetricsPreeclampsiaInternal medicinePharmacology

Abstract

fetched live from OpenAlex

This review addresses the maternal and perinatal benefits and risks of antihypertensive therapy in pregnancy. It covers the diagnosis of hypertension in pregnancy (with a brief discussion of ambulatory blood pressure measurement) followed by both the general principles of management of pregnancy hypertension and the specifics of individual antihypertensive drugs and drug classes. Discussion is focused on quantitative overviews of randomised, controlled trials, although observational literature is also discussed, particularly in reference to the potential teratogenicity of agents and the safety of their administration to nursing mothers. The treatment of severe hypertension is addressed separately from the treatment of mild-to-moderate hypertension, for which the maternal and fetal risks are substantially different.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.985
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.082
GPT teacher head0.363
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2004
Admission routes1
Has abstractyes

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