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Record W2108319506 · doi:10.1177/1073858410385870

Radial Glia: Progenitor, Pathway, and Partner

2011· review· en· W2108319506 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueThe Neuroscientist · 2011
Typereview
Languageen
FieldNeuroscience
TopicNeurogenesis and neuroplasticity mechanisms
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersCanadian Institutes of Health Research
KeywordsNeuroscienceSomaProgenitor cellNeuronBiologyDendrite (mathematics)ProgenitorNeurogenesisProcess (computing)NeurogliaCell biologyCentral nervous systemStem cellComputer science

Abstract

fetched live from OpenAlex

Radial glia (RG) are a glial cell type that can be found from the earliest stages of CNS development. They are clearly identifiable by their unique morphology, having a periventricular cell soma and a long process extending all the way to the opposite pial surface. Due to this striking morphology, RG have long been thought of as a transient substrate for neuron migration in the developing brain. In fact, RG cells, far from exclusively serving as a passive scaffold for cell migration, have a remarkably diverse range of critical functions in CNS development and function. These include serving as progenitors of neurons and glia both during development as well as in response to injury, helping to direct axonal and dendritic process outgrowth, and regulating synaptic development and function. RG also engage in extensive bidirectional signaling both with neurons and one another. This review describes the diversity of RG cell types in the CNS and discusses their many important activities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.969
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.149
GPT teacher head0.319
Teacher spread0.170 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it