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Record W2109654267 · doi:10.1017/s0043933907001559

Avian antimicrobial proteins: structure, distribution and activity

2007· article· en· W2109654267 on OpenAlexafffund
Olivier Wellman‐Labadie, Jaroslav Picman, Maxwell T. Hincke

Bibliographic record

VenueWorld s Poultry Science Journal · 2007
Typearticle
Languageen
FieldImmunology and Microbiology
TopicAntimicrobial Peptides and Activities
Canadian institutionsUniversity of Ottawa
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsAntimicrobialBiologyAntibiotic resistanceAntimicrobial peptidesInnate immune systemBacteriaMicrobiologyAntibioticsImmune systemImmunologyGenetics

Abstract

fetched live from OpenAlex

Antimicrobial proteins are active against protozoans, fungi, viruses as well as gram-positive and gram-negative bacteria. In many cases, antimicrobial proteins are present as components of innate immunity and are capable of evading bacterial resistance mechanisms. Due to these characteristics, these proteins represent an appealing alternative to conventional antibiotic drugs. Considerable research has been conducted on antimicrobial proteins from invertebrate and mammalian sources. Within the last decade, over 20 novel antimicrobial proteins have been isolated from avian systems. The majority of these proteins has been isolated from the domestic chicken and therefore represents a minuscule fraction of the avian antimicrobial proteins that are potentially awaiting discovery. In this review, we elaborate on these discoveries and on the future of avian antimicrobial protein research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.321
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.243
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations76
Published2007
Admission routes2
Has abstractyes

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