The E ffec ts of Cell Surface Proteins and Redox State on Platelet Aggregation and Adhesion
Bibliographic record
Abstract
Platelet aggregation is a complex process that results in side effects for patients with diabetes, atherosclerosis, stroke and heart attack. Although thoroughly studied, the details of the aggregation cascade are not determined. The mechanism for participation of protein disulfide isomerase (PDI) in platelet function has received attention in literature however has not been established. In addition, heat shock protein 70 (Hsp70) was found on the platelet surface and was investigated for its role in platelet aggregation. Thymosin was of interest as a potential effector in platelet aggregation. An additional goal of the study was further optimization of the flow cell chamber platelet aggregation model. UV-VIS Spectrophotometric and flow cell chamber data that indicate no significant effect of excess platelet surface PDI, b-b or Hsp70 on platelet aggregation and adhesion. However, Thymosin has been shown to positively affect rates of platelet aggregation at the doses of 1-10 g/mL.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".