A cellular automata based semi-automatic algorithm for segmentation of choroidal blood vessels from ultrahigh resolution optical coherence images of rat retina
Bibliographic record
Abstract
Abnormal changes in choroidal blood flow have been linked to various retinal diseases, such as Diabetic Retinopathy (DR) and Age related Macular Degeneration (AMD), which at later stages can lead to blindness. Therefore non-invasive and precise evaluation of choroidal blood flow can aid the diagnosis, treatment and monitoring of retinal disease progression. Doppler Optical Coherence Tomography is an imaging technique capable of measuring blood flow velocity and visualization of retinal and choroidal blood vessles. However accurate assessment of retinal and choroidal blood flow requires precise measurement of the blood vessel thickness. The presence of speckle noise and low image contrast of OCT tomograms makes this task very challenging. This paper proposes a cellular automata based semi-automatic algorithm for the segmentation of choroidal blood vessels. The proposed approach propagates user-defined points in order to identify the vessel boundaries, allowing a thickness profile to be extracted. The performance of the algorithm was tested on a series of retinal images acquired from living rats with a high speed, ultrahigh resolution OCT system (UHROCT). Experimental results show that the proposed approach provides precise thickness profiles even in the suboptimal conditions of low image contrast in the UHROCT images.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".