Acetylcholine Esterase Inhibitors in<i>Rhodiola rosea</i>
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The alcohol extract or Rhodiola rosea has been shown to cause 42 ± 3.2% inhibition of acetylcholine esterase (AChE) when tested at 10 g/L. This AChE inhibition provides a physiological explanation for the reported mental and memory enhancing properties of Rhodiola rosea extracts. Active guided fractionation indicated a multitude of components which are responsible for this plants AChE inhibition. Two flavonoid glycosides (gossypetin-7-O-l-rhamnopyranoside and rhodioflavonoside) were isolated and shown to cause 58 ± 15% and 38 ± 4% AChE inhibition respectively when tested at 5 g/L. In view of this new enzymatic activity and previous clinical work indicating memory and mental enhancing properties with no indication of toxicity, this plant needs to be researched for its potential at treating memory impairing disorders such as Alzheimer's disease.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it