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Record W2111476723 · doi:10.1093/database/bar032

NetSlim: high-confidence curated signaling maps

2011· article· en· W2111476723 on OpenAlexaff
Rajesh Raju, Vishalakshi Nanjappa, Lavanya Balakrishnan, Aparna Radhakrishnan, J.K. Thomas, Jyoti Sharma, Tian Mi, Shyam Mohan Palapetta, Tejaswini Subbannayya, Babylakshmi Muthusamy, Renu Goel, Yashwanth Subbannayya, Deepthi Telikicherla, M. Bhattacharjee, Sneha M. Pinto, Nazia Syed, M. Srikanth, Gajanan Sathe, Sartaj Ahmad, Sandip Chavan, Gaurav Kumar, Arivusudar Marimuthu, Thottethodi Subrahmanya Keshava Prasad, B. A. Rahiman, Osamu Ohara, Gary D. Bader, Siddharth Mohan, William P. Schiemann, Akhilesh Pandey

Bibliographic record

VenueDatabase · 2011
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBioinformatics and Genomic Networks
Canadian institutionsUniversity of Toronto
FundersScheme for Promotion of Academic and Research Collaboration
KeywordsComputer scienceVisualizationSet (abstract data type)Resource (disambiguation)Computational biologyDatabaseInformation retrievalData scienceWorld Wide WebData miningBiologyProgramming language

Abstract

fetched live from OpenAlex

We previously developed NetPath as a resource for comprehensive manually curated signal transduction pathways. The pathways in NetPath contain a large number of molecules and reactions which can sometimes be difficult to visualize or interpret given their complexity. To overcome this potential limitation, we have developed a set of more stringent curation and inclusion criteria for pathway reactions to generate high-confidence signaling maps. NetSlim is a new resource that contains this 'core' subset of reactions for each pathway for easy visualization and manipulation. The pathways in NetSlim are freely available at http://www.netpath.org/netslim.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.040
Threshold uncertainty score0.134

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0060.003
Science and technology studies0.0010.000
Scholarly communication0.0030.002
Open science0.0030.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0400.018

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.225
Teacher spread0.202 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations41
Published2011
Admission routes1
Has abstractyes

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