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Record W2112486825 · doi:10.1055/s-0037-1618202

ZNS-Vaskulitiden und entzündliche Hirnerkrankungen bei Kindern und Jugendlichen

2013· article· de· W2112486825 on OpenAlexaff
Susanne M. Benseler

Bibliographic record

VenueArthritis und Rheuma · 2013
Typearticle
Languagede
FieldMedicine
TopicAutoimmune Neurological Disorders and Treatments
Canadian institutionsAlberta Children's HospitalHospital for Sick Children
Fundersnot available
KeywordsGynecologyMedicine

Abstract

fetched live from OpenAlex

Zusammenfassung Schlaganfälle, Halluzinationen, Bewegungsstörungen und Krampfanfälle gehörten in der Vergangenheit nicht typischerweise zum Alltag der Kinderrheumatologen. Dies ändert sich gerade vielerorts. Unser Wissen um spezifische Entzündungsmechanismen und deren gezielte medikamentöse Behandlung macht uns zu wichtigen Partnern der Kinderneurologen, wenn es darum geht, Kinder und Jugendliche mit entzündlichen Hirnerkrankungen zu diagnostizieren und zu behandeln. Eine Entzündung des Gehirns kann im Rahmen einer Infektion, postinfektiös oder bei einer im Kindesalter eher selteneren systemischen Autoimmunerkrankung, wie beispielsweise einem systemischen Lupus erythematodes (SLE) oder einer Sarkoidose, auftreten. Ungleich häufiger jedoch erkranken vormals komplett gesunde Kinder und Jugendliche an einer isolierten oder primären Entzündung des Gehirns. Zielstrukturen können zerebrale Gefäße, Neurone oder spezifische Oberflächenrezeptoren des Gehirns sein. Die Entzündung hat schwere neurologische oder psychiatrische Symptome zur Folge, die im Entzündungsstadium selbst reversibel sind. Nur die frühzeitige Diagnose und gezielte Behandlung im interdisziplinären Team kann eine irreversible Hirnschädigung verhindern.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.007
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.268
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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