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Record W2114119317 · doi:10.5539/ijc.v2n2p149

Synthesis and Antibacterial Activity of Novel Organoselenium Compounds

2010· article· en· W2114119317 on OpenAlexvenueno aff
P. M. Radhakrishna, K.C. Sharadamma, H. M. Vagdevi, P. M. Abhilekha, Rubeena Mubeen S., K. Nischal

Bibliographic record

VenueInternational Journal of Chemistry · 2010
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicOrganoselenium and organotellurium chemistry
Canadian institutionsnot available
Fundersnot available
KeywordsChemistryPropanoic acidBacillus subtilisStaphylococcus aureusAntibacterial activityAcetic acidEscherichia coliMinimum inhibitory concentrationBacteriaProton NMROrganic chemistryAntimicrobialBiochemistry

Abstract

fetched live from OpenAlex

Organoselenium compounds are known to possess antioxidant, anticancer and antibacterial activities. In the present study, 3-[(phenylcarbonyl)selenyl]propanoic acid was synthesized and different ester derivatives of 3-[(phenylcarbonyl)selenyl]propanoic acid and benzoylselenoglycolic acid were synthesized and characterized using IR, NMR and Mass spectroscopy. Minimum Inhibitory Concentration (MIC) of the newly synthesized compounds was determined against gram positive and gram negative bacteria. Some of the compounds showed moderate to significant activity against Staphylococcus aureus, Salmonella typhimurium, Escherichia coli and Bacillus cereus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.365
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2010
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of ChemistrySame topicOrganoselenium and organotellurium chemistryFrench-language works237,207