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Actinidic Archaea Mediates Biological Transmutation in Human Systems- Experimental Evidence

2012· article· en· W2114162833 on OpenAlexvenueno aff
Ravikumar Kurup, Parameswara Achutha Kurup

Bibliographic record

VenueAdvances in natural science/Advances in natural sciences · 2012
Typearticle
Languageen
FieldMedicine
TopicKidney Stones and Urolithiasis Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsCalciumMagnesiumArchaeaMineralization (soil science)BiologyBacteriaBiochemistryBiological activityChemistryMicrobiologyIn vitroEcologyGenetics

Abstract

fetched live from OpenAlex

Abstract Background: Actinidic archaea has been described in human systems from our laboratory and function as cellular endosymbionts regulating multiple cellular functions. The actinidic archaea is an endosymbiont of the human cell and it is possible that the organism can mediate biological transmutation. The actinidic archaea can exist as nanoarchaea which can undergo magnetite and calcium mineralization. It is possible that magnesium is being transmuted biologically to calcium to produce amounts sufficient for calcium mineralization. Calcified nanoarchaea can produce a systemic immune activation contributing to the diverse pathologies. Methods: Experimental system for demonstrating biological transmutation by archaea was as follows: The basic system contained patient’s serum 0.5 ml + normal serum 0.25 ml + physiological buffered saline + cerium chloride 0.1 mg/ml. To the basic system MgSO4 0.1 mg/ ml was added. The Mg++ and Ca++ were estimated at 0 hour. The remaining portion was incubated for 16 hours at 37 oC for 16 hours. The Mg++ and Ca++ were estimated at the end of 16 hours. The estimation of Mg++ and Ca++ were done by using commercial kits. Cytochrome F420 was estimated flourimetrically (excitation wavelength 420 nm and emission wavelength 520 nm). Results: The results showed that there was a decrease in magnesium and a concomitant increase in calcium in incubated serum samples from normal individuals. The percentage decrease in magnesium was 15.68 to 31.48%. The percentage increase in calcium was 10.43 to 9.79%. There was detection of cytochrome F420 in the system by fluorescence indicating archaeal growth dependent on actinidic cerium. This showed that the actinidic archaea was mediating the biological transmutation of magnesium to calcium. Conclusions: The actinidic archaea can mediate magnesium to calcium transmutation. The transmutation altered calcium-magnesium ratios in the cell can alter synaptic transmission, mitochondrial function, golgi body/ ER function, lysosomal function, immune activation, cell proliferation, insulin resistance and cell death. Key words : Archaea; Actinides; Calcium; Magnesium; Transmutation

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.401
Teacher spread0.364 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes1
Has abstractyes

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