Radiation exposure differentially affects songbird 8-hydroxy-2′-deoxyguanosine plasma profiles: Ionizing radiation damage response in songbirds
Bibliographic record
Abstract
The importance of understanding the effects of radiation exposure on wildlife is a critical responsibility of our stewardship of nuclear energy production. We tested the hypothesis that songbirds respond to exogenous radiation exposure with changes in plasma 8-hydroxy-2'-deoxyguanosine (8-OH-dG). We exposed two species of songbirds, house sparrows (Passer domesticus; n = 12) and song sparrows (Melospiza melodia; n = 12), to one of four acute whole-body radiation treatments: 75, 150, 300, or 600 mGy. We measured DNA damage by proxy as 8-OH-dG levels in the plasma at 0 hr (baseline), 36 hr, and 7 days post radiation. For both species, at all radiation treatments, 8-OH-dG levels increased significantly 36 hr following radiation exposure. However, songbird species differed significantly in response to treatment across time and between treatment groups. Song sparrows showed no significant changes in 8-OH-dG levels between 36 hr and Day 7. In contrast, house sparrows exposed to 300 and 600 mGy had significantly increased 8-OH-dG levels at Day 7 compared with 36 hr. This study demonstrates that in a controlled experiment, in isolation from other sources of genotoxicity, radiation exposure significantly affects songbirds. Our results suggest future research examining the effects of radiation on songbirds must consider using multiple species to assess the biological effects of radiation, as different species can show strikingly different responses to radiation dosage across time.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".