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Record W2115114484 · doi:10.1109/nebc.2007.4413362

Nanotechnology-derived hydrogels for cardiac tissue replacement

2007· article· en· W2115114484 on OpenAlexfundno aff
Ashwini Ranjan, Thomas J. Webster

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicTissue Engineering and Regenerative Medicine
Canadian institutionsnot available
FundersNational Institutes of HealthMcMaster University
KeywordsBiomaterialTissue engineeringSelf-healing hydrogelsIn vivoBiomedical engineeringTissue DonationOrgan donationTransplantationComputer scienceMedicineMaterials scienceSurgeryBiologyBiotechnology

Abstract

fetched live from OpenAlex

The national organ transplant waiting list is growing five times faster than the rate of organ donation, indicating a need to provide a more plentiful source of tissue replacements. Furthermore, the national number one cause for human death is heart disease. Because of the high percentage of heart failure and a low number of successful organ donations, studies are now focusing on the design of new generation biomaterials and functional tissue constructs for specialized tissue repair and replacement. Developing such biomaterials requires the fabrication of scaffolds that mimic in vivo extracellular matrices (ECM). The objective of this study was to design a 'smart' biomaterial that mimics conditions in vivo, creating a micro-and nano-environment suitable for healthy cardiac tissue growth and function.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.293
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

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