MétaCan
Menu
Back to cohort
Record W2115177951 · doi:10.1177/108925320200600109

Fat Embolism: A Central Nervous System Problem

2002· article· en· W2115177951 on OpenAlexaff
Robert J. Byrick

Bibliographic record

VenueSeminars in Cardiothoracic and Vascular Anesthesia · 2002
Typearticle
Languageen
FieldMedicine
TopicCardiac Arrest and Resuscitation
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineFat embolismCardiopulmonary bypassMagnetic resonance imagingIschemiaInflammationFat embolism syndromeEdemaNeurocognitiveCardiologyCerebral circulationIschemic injuryInternal medicineAnesthesiaRadiologyCognition

Abstract

fetched live from OpenAlex

Microvascular fat in the systemic circulation is a common postmortem finding in patients dying after trauma or cardiopulmonary bypass. The causative relationship between the microvascular fat and tissue inflammation, ischemia, and injury is unclear. Characteristic clinical lesions on magnetic resonance imaging and evidence in animal models suggest that focal cerebral edema may be associated with fat microemboli. This fat occludes cerebral vessels 5-15 microns in diameter, after passing through either the lung or filters in cardiopulmonary bypass circuits. Microvascular fat may directly cause the injury or may be a ‘second hit’ phenomenon, thus aggravating a pre-existing inflammatory reaction to injury, indirectly causing cerebral injury and adverse neurocognitive outcomes after cardiac surgery and trauma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.313
Threshold uncertainty score0.792

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.237
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2002
Admission routes1
Has abstractyes

Explore more

Same venueSeminars in Cardiothoracic and Vascular AnesthesiaSame topicCardiac Arrest and ResuscitationFrench-language works237,207