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Rivastigmine for Dementia Associated with Parkinson's Disease

2004· article· en· 1,217 citations· W2115455636 on OpenAlex· 10.1056/nejmoa041470

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Classifier prediction

metacan-v1-d91a1de5be90

Predictions imitate two machine teachers. Scores are not calibrated prevalence probabilities.

Classifier candidate
Randomized trialNon-randomized trialObservationalCase reportTheoretical or conceptualNot applicable
Classifier consensus
Randomized trialObservationalCase report
Teacher imitation scores

Codex

Other design0.835
Observational0.217
Randomized trial0.037
Case report0.033
Not applicable0.005
Theoretical or conceptual0.003
Metaresearch0.003
Bench or experimental0.001
Bibliometrics0.001
Systematic review0.000
Meta-analysis0.000
Open science0.000
Research integrity0.000
Simulation or modelling0.000
Science and technology studies0.000
Qualitative0.000
Meta-epidemiology (narrow)0.000
Meta-epidemiology (broad)0.000
Scholarly communication0.000
Non-randomized trial0.000

Gemma

Randomized trial0.524
Observational0.396
Not applicable0.087
Case report0.073
Theoretical or conceptual0.031
Non-randomized trial0.021
Metaresearch0.002
Systematic review0.001
Bibliometrics0.000
Meta-analysis0.000
Meta-epidemiology (broad)0.000
Bench or experimental0.000
Open science0.000
Simulation or modelling0.000
Scholarly communication0.000
Research integrity0.000
Science and technology studies0.000
Meta-epidemiology (narrow)0.000
Qualitative0.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.020
GPT teacher head0.299
Teacher spread
0.278 how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

BACKGROUND

Cholinergic deficits are prominent in patients who have dementia associated with Parkinson's disease. We investigated the effects of the dual cholinesterase inhibitor rivastigmine in such patients.

METHODS

Patients in whom mild-to-moderate dementia developed at least 2 years after they received a clinical diagnosis of Parkinson's disease were randomly assigned to receive placebo or 3 to 12 mg of rivastigmine per day for 24 weeks. Primary efficacy variables were the scores for the cognitive subscale of th…

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