Thyroid replacement therapy and atrial fibrillation in acute ischemic stroke
Bibliographic record
Abstract
Atrial fibrillation is a risk factor for ischemic stroke.1 Hyperthyroidism is a cause of atrial fibrillation. Subclinical hyperthyroidism, also associated with atrial fibrillation, may result from excess thyroid replacement therapy.2,3 However, it is unclear whether thyroid replacement therapy is a risk factor for atrial fibrillation in patients with acute ischemic stroke. In this case-control study, we sought to determine the association between thyroid replacement therapy and atrial fibrillation in patients presenting with ischemic stroke. The study protocol was approved by the local Institutional Research Board at Stanford University Medical Center. We identified consecutive patients with ischemic stroke with atrial fibrillation (cases) and without atrial fibrillation (controls) admitted to the Stanford Stroke Center between 1996 and 2004 through a local stroke registry database. The stroke registry (3,276 subjects) includes patients presenting with ischemic stroke, TIA, hemorrhagic stroke, and patients in whom stroke was suspected but …
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".