Cortisol and GH: odd and controversial ideas
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Activation of the hypothalamo-pituitary-adrenal (HPA) axis and of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis represents a physiological response to the energetic, metabolic, vascular, and sometimes neurophysiologic or psychological needs of exercise. Long-lasting increased and (or) decreased secretion of cortisol (the end-product of the HPA axis) or of GH is detrimental to health. This suggests that the activity of these hormonal axes is finely tuned toward homeostasia, tolerating limited prolonged homeostatic disruption. However, the relationships between exercise training and cortisol and GH secretion are full of odd and controversial ideas. In this review, the relationships between HPA axis adaptation to exercise training or disadaptation with overtraining will be discussed, with an emphasis on the limitation on the current measures used to profile hormonal activity. Knowledge of these relationships between cortisol and GH responses to exercise is an important tool to fight against doping with glucocorticoids and GH, and their health-damaging consequences.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it