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Record W2118384803 · doi:10.1172/jci13397

The multiple contributions of thyroid hormone to heat production

2001· letter· en· W2118384803 on OpenAlexaff
J. Enrique Silva

Bibliographic record

VenueJournal of Clinical Investigation · 2001
Typeletter
Languageen
FieldEnvironmental Science
TopicPhysiological and biochemical adaptations
Canadian institutionsJewish General Hospital
Fundersnot available
KeywordsHomeothermyPoikilothermFacultativeThermogenesisThermoregulationSet pointThermodynamicsBiologyChemistryEcologyEndocrinologyPhysics

Abstract

fetched live from OpenAlex

The advent of homeothermy during evolution brought with it the need of mechanisms to produce heat to maintain body temperature in environments usually colder than the body. Thermogenic mechanisms are customarily classified as either obligatory or facultative. Obligatory thermogenesis (OT) represents the energy dissipated as heat in the many energetic transformations inherent to life. As discussed below, OT may be higher in warm-blooded species, possibly reflecting a lower thermodynamic efficiency of homeothermic machine compared with the poikilothermic machine. Facultative, or adaptive, thermogenesis (FT) is the additional heat production that the body activates in response to cold or overfeeding. The magnitude of OT determines the thermoneutrality temperature — the environmental temperature at which FT is activated, at which point neither heat-producing nor heat-dissipating mechanisms are activated, and body temperature is maintained solely on the basis of OT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.064
GPT teacher head0.325
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations66
Published2001
Admission routes1
Has abstractyes

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