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Record W2119693473 · doi:10.1186/1472-6882-12-s1-p204

P02.148. Assessing interactions between herbal medicines and drugs: updated review

2012· article· en· W2119693473 on OpenAlexaff
Lauren Girard, Candace Necyk, Simran Jassar, A Filipelli, Paula Gardiner, Heather Boon, Sunita Vohra

Bibliographic record

VenueBMC Complementary and Alternative Medicine · 2012
Typearticle
Languageen
FieldMedicine
TopicComplementary and Alternative Medicine Studies
Canadian institutionsUniversity of TorontoUniversity of Alberta
Fundersnot available
KeywordsMedicineMedical prescriptionAlternative medicinePaceTraditional medicinePharmacology

Abstract

fetched live from OpenAlex

Three databases (Medline, Embase, and International Pharmaceutical Academy) were searched for studies conducted from 2007-2010 pertaining to NHP-drug interactions. In addition, National Medicines Comprehensive Database (NMCD) was searched in July 2011. As a cross check tool to verify that no interaction was overlooked, “Herb, nutrient, and drug interactions: clinical implications and therapeutic strategies” (Stargrove et al, 2008) was reviewed to find literature pertaining to NHP-drug interactions. Potentially relevant studies were identified from the primary and secondary literature, and if an interaction was found, the interaction was verified by a second reviewer. To date, 1997 studies have been identified from the database search (1910), textbook and NMCD (87) and screened for interactions. Examination of these studies for interactions is ongoing. This update is intended to increase the knowledge about NHP-drug interactions as well as to fill in any gaps that may have been overlooked in construction of the original tool. The NHP-drug interaction tool is intended to act as a quick guide for users of NHPs and pharmaceuticals in order to avoid adverse reactions. Future steps in this project will include further updates to the tool as well as creating specific grids for different clinical specialties.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.258
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.131
GPT teacher head0.433
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2012
Admission routes1
Has abstractyes

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