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Record W2119851749 · doi:10.1093/annonc/mdv004

Prevalence of theHOXB13 G84E germline mutation in British men and correlation with prostate cancer risk, tumour characteristics and clinical outcomes

2015· article· en· W2119851749 on OpenAlexaff
Zsofia Kote‐Jarai, Christos Mikropoulos, Daniel Leongamornlert, Tokhir Dadaev, Malgorzata Tymrakiewicz, Edward J. Saunders, Michael E. Jones, Sarah Jugurnauth-Little, Koveela Govindasami, Michelle Guy, Freddie C. Hamdy, Jenny Donovan, David E. Neal, J. Athene Lane, David P. Dearnaley, Rosemary Wilkinson, Emma Sawyer, Angela Morgan, Antonis C. Antoniou, Rosalind A. Eeles, Per Hall, Andrew Berchuck, Joe Dennis, Alison M. Dunning, Andrew Lee, Ed Dicks, Jacques Simard, Daniel C. Tessier, François Bacot, Daniel Vincent, Sylvie LaBoissière, Frederic Robidoux, Stig E. Bojesen, Sune F. Nielsen, Børge G. Nordestgaard

Bibliographic record

VenueAnnals of Oncology · 2015
Typearticle
Languageen
FieldMedicine
TopicProstate Cancer Diagnosis and Treatment
Canadian institutionsInstitute of Cancer Research
FundersNational Institute for Health and Care ResearchCancer Research UK
KeywordsMedicineProstate cancerInternal medicineOdds ratioOncologyProstate-specific antigenConfidence intervalSingle-nucleotide polymorphismMissense mutationPopulationGermline mutationFamily historyCancerGynecologyGenotypeMutationGeneticsGene

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.104
Threshold uncertainty score0.244

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.068
GPT teacher head0.406
Teacher spread0.338 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations98
Published2015
Admission routes1
Has abstractno

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