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Record W2120095382 · doi:10.1093/molbev/msr024

An X-Linked Haplotype of Neandertal Origin Is Present Among All Non-African Populations

2011· article· en· W2120095382 on OpenAlexafffund
V. Yotova, J Lefebvre, Claudia Moreau, Elias Gbeha, Kristine Hovhannesyan, Stéphane Bourgeois, Sandra Bédarida, Luı́sa Azevedo, António Amorim, Tamara Sarkisian, Patrice Hodonou Avogbe, Nicodème Chabi, Mamoudou H. Dicko, E. S. Kou' Santa Amouzou, A. Sanni, June Roberts-Thomson, B. Boettcher, Rodney J. Scott, Damian Labuda

Bibliographic record

VenueMolecular Biology and Evolution · 2011
Typearticle
Languageen
FieldSocial Sciences
TopicPleistocene-Era Hominins and Archaeology
Canadian institutionsUniversité de MontréalCentre Hospitalier Universitaire Sainte-Justine
FundersFundação para a Ciência e a TecnologiaCanadian Institutes of Health ResearchUniversidade do Porto
KeywordsBiologyHomo sapiensOut of africaEvolutionary biologyHaplotypePopulationColonizationFounder effectGenomeGeneticsGeneEcologyDemographyArchaeologyAlleleGeography

Abstract

fetched live from OpenAlex

Recent work on the Neandertal genome has raised the possibility of admixture between Neandertals and the expanding population of Homo sapiens who left Africa between 80 and 50 Kya (thousand years ago) to colonize the rest of the world. Here, we provide evidence of a notable presence (9% overall) of a Neandertal-derived X chromosome segment among all contemporary human populations outside Africa. Our analysis of 6,092 X-chromosomes from all inhabited continents supports earlier contentions that a mosaic of lineages of different time depths and different geographic provenance could have contributed to the genetic constitution of modern humans. It indicates a very early admixture between expanding African migrants and Neandertals prior to or very early on the route of the out-of-Africa expansion that led to the successful colonization of the planet.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.073
Threshold uncertainty score0.518

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.333
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations68
Published2011
Admission routes2
Has abstractyes

Explore more

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