Secular Trends and Senescence of Blood Pressure in a Japanese and Yugoslavian Cohort of the Seven Countries Study
Why this work is in the frame
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Bibliographic record
Abstract
The aim of this study was to: (i) separately estimate the effects of secular trends and senescence from the blood pressure (BP) data of a cohort follow-up study, and (ii) compare cohort and population stroke mortality trends with systolic blood pressure (SBP) senescence (aging) and secular trends. The data for this work came from a Japanese (n = 508 men) and a Yugoslavian cohort (n = 552 men) of the Seven Countries Study. This report is restricted to one cohort of each country for reason of data availability. Our analysis showed that BP rose with age even after correcting for the secular trends. A significant difference in SBP rise with age was found between Yugoslavian and Japanese cohorts (0.8 vs 1.4 mmHg/year, p = 0.0001). The secular and aging trends in SBP were significantly associated with the cohort and population stroke mortality in both cohorts. In conclusion, our results suggest that BP change with age does not result exclusively from biological aging; other factors also participate in the process. The rate of BP rise with age differs in two ethnically different populations. Difference in arterial stiffness and/or dietary salt intake between these populations may account for this observation.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it