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Record W2121683038

Rheumatoid arthritis : of mice and men : towards the development of innovative therapies for rheumatoid arthritis

2008· article· en· W2121683038 on OpenAlexaff
Daniëlle M. Gerlag

Bibliographic record

VenueUvA-DARE (University of Amsterdam) · 2008
Typearticle
Languageen
FieldMedicine
TopicMonoclonal and Polyclonal Antibodies Research
Canadian institutionsInstitute of Infection and Immunity
FundersUniversity of California, San DiegoDutch Arthritis AssociationNederlandse Organisatie voor Wetenschappelijk OnderzoekNational Institutes of HealthUniversiteit van AmsterdamDeutsche ForschungsgemeinschaftAstraZeneca
KeywordsRheumatoid arthritisMedicineImmunologyIntensive care medicine
DOInot available

Abstract

fetched live from OpenAlex

General introduction 11 Rheumatoid arthritisRheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease of unknown etiology affecting about 1% of the population worldwide.The clinical syndrome is characterized by swelling, pain, and limited motion of multiple joints, due to inflammation of the synovial tissue lining the inside of the joints.The inflamed tissue, known as pannus, invades into the cartilage and bone, resulting in progressive joint destruction leading to deformity of the joints, permanent disability, and loss of quality of life (1).Despite current treatments, the disease is still associated with long-term morbidity and early mortality (2).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.002
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.252
Teacher spread0.218 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2008
Admission routes1
Has abstractno

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