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Record W2123288878 · doi:10.3747/co.19.1007

Prognostic Effect of Early Treatment of Paraneoplastic Limbic Encephalitis in a Patient with Small-Cell Lung Cancer

2012· article· en· W2123288878 on OpenAlexaffvenue
Nafisha Lalani, Rashida Haq

Bibliographic record

VenueCurrent Oncology · 2012
Typearticle
Languageen
FieldMedicine
TopicAutoimmune Neurological Disorders and Treatments
Canadian institutionsPrincess Margaret Cancer CentreSt. Michael's Hospital
Fundersnot available
KeywordsLimbic encephalitisMedicineMalignancyLimbic systemLung cancerCancerDiseasePersonality changesPathologyLungEncephalitisImmunologyCentral nervous systemInternal medicineVirus

Abstract

fetched live from OpenAlex

Paraneoplastic neurologic syndrome (pns) is an uncommon manifestation of cancer and may present before any symptoms of malignant disease. This syndrome occurs in fewer than 1 of every 10,000 patients diagnosed with a malignancy. Anti-neural antibodies have been associated with pns, suggesting that this condition may reflect immune mechanisms. Depending on the region of the nervous system that has been affected, pns can have a number of manifestations. Paraneoplastic limbic encephalitis (ple) stems from involvement of the limbic system and may present with seizures and changes in mood, memory, and personality. The present report describes the case of a 55-year-old man presenting with ple in the setting of small-cell lung cancer, with subsequent improvement of his neurologic symptoms. The value of rapid diagnosis and multidisciplinary management of this syndrome are discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.067
Threshold uncertainty score0.449

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.349
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2012
Admission routes2
Has abstractyes

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