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Record W2124623507 · doi:10.5897/jciir.9000003

Benign monoclonal gammopathy in a dog exhibiting a low antibody titer to Ehrlichia canis

2010· article· en· W2124623507 on OpenAlexaffabout
Ng Stephanie, Sophia Lim, Allison Daub, Surinder S. Saini, Kaushik K. Azad

Bibliographic record

VenueJournal of Clinical Immunology and Immunopathology Research · 2010
Typearticle
Languageen
FieldImmunology and Microbiology
TopicVector-borne infectious diseases
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsEhrlichia canisGammopathyMonoclonal gammopathyCanisMedicineMonoclonal antibodyTiterMonoclonalImmunologyPathologyVirologyAntibodySerologyBiology

Abstract

fetched live from OpenAlex

The occurrence of a remarkable benign g-monoclonal gammopathy in a 2.5-year-old intact male bichon frise dog, secondary to acute Ehrlichia canis infection, with no travel history outside of Ontario. Exceptionally high levels of serum IgG (104.0 g/L) as a result of benign monoclonal gammopathy were noted during the disease state that returned to normal subsequent to recovery. Treatment with doxycyline and prednisone resulted in complete recovery and disappearance of the monoclonal gammopathy. In conclusion, such a recovery from monoclonal gammopathy due to infection is indeed promising since very high serum IgG concentrations can be brought back to physiological levels by therapeutic intervention.   Key words: Dog, benign monoclonal gammopathy, Ehrlichia canis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.426
Teacher spread0.380 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2010
Admission routes2
Has abstractyes

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