Bibliographic record
Abstract
Abstract Cirrhotic cardiomyopathy is generally defined as subnormal ventricular response to stress in the face of high resting cardiac output. Although this syndrome was first noticed more than three decades ago in cirrhotic patients, it was originally ascribed to latent alcoholic cardiomyopathy. During the 1980s−1990s, it became clear that blunted ventricular contractility to stress is also present in non‐alcoholic patients and animal models of cirrhosis. Mechanistic studies in experimental animal models of cirrhosis indicate that multiple factors are responsible, including abnormal biophysical membrane characteristics, impaired β‐adrenergic signal transduction and increased activity of cardiodepressant systems mediated by cGMP. Cirrhotic cardiomyopathy appears to be precipitated or worsened by liver transplantation, insertion of transjugular intrahepatic portosystemic stent‐shunts and infections. It may play a role in the pathogenesis of hepatorenal syndrome. Current management recommendations are empiric, non‐specific measures; further research in this area is needed.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".