Age no barrier to diagnosis
Bibliographic record
Abstract
John was 14 years old when he was referred by his general practitioner (GP) with generalised stiffness in his legs and wrists for the past 4 days. His GP noted that his temperature was 39.5°C and had been raised for 2 days. John also complained of having had a frontal headache the previous day which had now resolved. There was minimal past medical history though John had been diagnosed with ocular hypertension 2 years prior to current presentation which was currently being monitored; however, he was not on any ongoing treatment for this. John had no known contact history and his immunisations were up to date. His mother was Japanese and his father was Caucasian. On examination John was alert and orientated. His conjunctivae were both injected but they were not itchy or painful and there was no exudate. John had a cold sore on the right side of his mouth, which appeared to have almost resolved. His lips were not red but were peeling (fig 1). There were no intra-oral ulcers. He was noted to have minimal cervical lymphadenopathy on the right. Figure 1 Picture of mouth demonstrating the oral changes. John’s throat was noted to be “pink” with no tonsillar enlargement or exudate. John’s blood pressure was 121/74 mmHg and his temperature was 39.2°C. His chest was clear and heart sounds normal. His neurological examination was normal with no neck stiffness. John’s wrists and lower legs were both stiff. His right knee appeared swollen and had limited flexion and extension. His right ankle had limited range of movements but no swelling. On his left leg there was a 3 cm × 4 cm erythematous region which was not tender or itchy. Within this area there was a smaller raised area which blanched. There were three smaller similar lesions on his …
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.019 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.003 | 0.003 |
| Open science | 0.001 | 0.003 |
| Research integrity | 0.003 | 0.003 |
| Insufficient payload (model declined to judge) | 0.483 | 0.202 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".