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Frailty in Relation to the Accumulation of Deficits

2007· review· en· 2,959 citations· W2129700906 on OpenAlex· 10.1093/gerona/62.7.722

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Abstract

This review article summarizes how frailty can be considered in relation to deficit accumulation. Recalling that frailty is an age-associated, nonspecific vulnerability, we consider symptoms, signs, diseases, and disabilities as deficits, which are combined in a frailty index. An individual's frailty index score reflects the proportion of potential deficits present in that person, and indicates the likelihood that frailty is present. Although based on a simple count, the frailty index shows several interesting properties, including a characteristic rate of accumulation, a submaximal limit, and characteristic changes with age in its distribution. The frailty index, as a state variable, is able to quantitatively summarize vulnerability. Future studies include the application of network analyses and stochastic analytical techniques to the evaluation of the frailty index and the description of other state variables in relation to frailty.

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The record

Venue
The Journals of Gerontology Series A
Topic
Frailty in Older Adults
Field
Medicine
Canadian institutions
Dalhousie University
Funders
Keywords
Frailty IndexIndex (typography)Vulnerability (computing)GerontologyRelation (database)Variable (mathematics)EconometricsMedicineStatisticsComputer scienceMathematicsData miningComputer security
Has abstract in OpenAlex
yes