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Record W2132042341 · doi:10.1098/rspa.2007.0097

Justification for wavefront propagation in a tumour growth model with contact inhibition

2008· article· en· W2132042341 on OpenAlexaff
Huiyan Zhu, Wei Yuan, Chunhua Ou

Bibliographic record

VenueProceedings of the Royal Society A Mathematical Physical and Engineering Sciences · 2008
Typearticle
Languageen
FieldMathematics
TopicMathematical Biology Tumor Growth
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsContact inhibitionCancer cellNonlinear systemWavefrontDiffusionMathematicsCellMathematical analysisPhysicsChemistryOpticsCancerMedicineInternal medicineQuantum mechanics

Abstract

fetched live from OpenAlex

Cancer is a disease characterized by abnormal division of cells combined with the malignant behaviour of these cells. Malignant cancer cells tend to spread, either by direct growth into adjacent tissue through invasion and dispersal or by implantation into distant sites by metastasis. In this paper, we will concentrate on the first type of tumour growth and consider a reaction–diffusion model for competition cells with nonlinear diffusion term modelling contact inhibition between normal and tumour cell populations for which wave propagation is usually observed in clinical data. Mathematically, based on a combination of perturbation methods, the Fredholm theory and the Banach fixed point theorem, we theoretically justify the existence of the travelling wave solution. Numerical simulations are finally illustrated to confirm our rigorous results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.640
Threshold uncertainty score0.381

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.236
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2008
Admission routes1
Has abstractyes

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