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Record W2132257110 · doi:10.1002/anie.201007018

Controlled Self‐Assembling of Gadolinium Nanoparticles as Smart Molecular Magnetic Resonance Imaging Contrast Agents

2011· article· en· W2132257110 on OpenAlexafffund
Gaolin Liang, John A. Ronald, Yuanxin Chen, Deju Ye, Prachi Pandit, Man Lung, Brian K. Rutt, Jianghong Rao

Bibliographic record

VenueAngewandte Chemie International Edition · 2011
Typearticle
Languageen
FieldMaterials Science
TopicLanthanide and Transition Metal Complexes
Canadian institutionsWestern University
FundersNational Cancer InstituteCanadian Institutes of Health Research
KeywordsLibrary scienceMolecular imagingNuclear medicineMedicineComputer science

Abstract

fetched live from OpenAlex

Gd smart: MRI contrast agents are presented that are based on a biocompatible condensation reaction. Upon reduction, a gadolinium-containing cell-permeable small-molecule probe condenses into cyclic oligomers that subsequently self-assemble into nanoparticles (NPs) with enhanced relaxivity (by 110 % at 1.5 T and 35 °C, and 104 % in live cells at 0.5 T).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.256
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations156
Published2011
Admission routes2
Has abstractyes

Explore more

Same venueAngewandte Chemie International EditionSame topicLanthanide and Transition Metal ComplexesFrench-language works237,207