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Record W2132581407 · doi:10.1186/1471-2202-15-s1-p48

Structured chaos shapes joint spike-response noise entropy in temporally driven balanced networks

2014· article· en· W2132581407 on OpenAlexafffund
Guillaume Lajoie, Jean‐Philippe Thivierge, Eric Shea‐Brown

Bibliographic record

VenueBMC Neuroscience · 2014
Typearticle
Languageen
FieldNeuroscience
TopicNeural dynamics and brain function
Canadian institutionsUniversity of Ottawa
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchUniversity of WashingtonBurroughs Wellcome FundNational Institutes of HealthNational Science Foundation
KeywordsSpike (software development)Computer scienceStatistical physicsSpike trainNoise (video)CHAOS (operating system)Joint (building)Entropy (arrow of time)Artificial intelligencePhysics

Abstract

fetched live from OpenAlex

How variable and noisy is the neural code arising from the joint activity of recurrently connected cells? Isolated neurons are known to respond to fluctuating input currents with reliable spike patterns [1,2], but variability in stimulus-evoked spike trains is increasingly pronounced in deeper, more recurrently connected brain areas such as cortex [3]. What are the network-level sources of this variability, and how they might constrain spiking features relevant for coding remains an open question. We focus on spiking model networks with sparse, random connectivity and balanced excitation and inhibition that reproduce the irregular firing that typifies cortical activity. In such models, activity is known to be chaotic, with extremely strong sensitivity of spike outputs on tiny changes in a network’s initial conditions [4-6]. Nevertheless, when subject to temporally fluctuating driving inputs, networks can have chaotic attractors of limited dimension and geometric properties leading to reduced spiking variability at the single-cell level [7]. As recent studies suggest that the impact of noise on network coding cannot be understood by single cell properties alone [8,9], we study mechanisms underlying the joint activity of entire networks. We derive a bound for the entropy of joint spike pattern distributions in large spiking model networks in response to a fluctuating temporal signal. The analysis is based on results from random dynamical systems theory and complimented by detailed numerical simulations. We find that despite very weak conditional correlations between neurons, the resulting joint variability of network responses is surprisingly lower than what would be expected by considering only limited statistical neural interactions. Moreover, joint spiking variability is strongly constrained by the level of temporal features of input stimuli.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.932
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.243
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes2
Has abstractyes

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