MétaCan
Menu
Back to cohort
Record W2134889459 · doi:10.1080/09603120802415818

Oral exposure of mice to formulations of organophosphorous pesticides: gestational and litter outcomes

2009· article· en· W2134889459 on OpenAlexaff
James Gomes, O L Lloyd

Bibliographic record

VenueInternational Journal of Environmental Health Research · 2009
Typearticle
Languageen
FieldEnvironmental Science
TopicEffects and risks of endocrine disrupting chemicals
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsLitterGestationPesticideFetusCaesarean sectionToxicologyAnimal scienceBiologyPregnancyPhysiologyEcology

Abstract

fetched live from OpenAlex

The purpose of this study was to examine gestational and litter outcomes in mice models from oral exposure to a mixture of formulations of organophosphorous pesticides used in local vegetable production. Male and female mice were exposed to premating and preconception, respectively, to a mixture of organophosphorous pesticide formulations for a period of 7 weeks. The pregnant dams were monitored during gestation and delivered by Caesarean section pre-partum. The percentages of resorptions and the resorptions/implantations ratios, in all the exposed groups, were significantly higher than the reference and the control groups. Percentages of litters with one or more lost embryos were observed in all the exposed groups and were significantly higher than the comparison groups. Fetal weights were significantly lower and the maternal weight gains per live fetus were significantly higher in the medium-dose-exposed groups than the control group. Percentages of fetuses with intra-uterine growth retardation at one standard deviation were significantly higher in all the exposed groups than the comparison groups.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.289
Threshold uncertainty score0.422

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.455
Teacher spread0.414 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2009
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of Environmental Health ResearchSame topicEffects and risks of endocrine disrupting chemicalsFrench-language works237,207