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Record W2135706959 · doi:10.1080/07357900902996441

Cancer and Thrombosis: Back to the Future<i>Renewed Interest in an Old Problem</i>

2009· letter· en· W2135706959 on OpenAlexaff
Gary H. Lyman, Alok A. Khorana, Nicole M. Kuderer, Agnes Y. Lee

Bibliographic record

VenueCancer Investigation · 2009
Typeletter
Languageen
FieldMedicine
TopicVenous Thromboembolism Diagnosis and Management
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineCancerThrombosisAmbulatoryRandomized controlled trialVenous thromboembolismMetastasisIntensive care medicineSurgeryInternal medicineOncology

Abstract

fetched live from OpenAlex

Cancer patients are at increased risk for thromboembolic complications due to the release of procoagulants, compression or invasion of blood vessels and the reduced mobility associated with cancer and cancer treatment. This has led to recommendations for thromboprophylaxis in hospitalized medical and surgical cancer patients and extended prophylaxis in cancer patients experiencing a venous thromboembolism. Routine prophylactic anticoagulation is not currently recommended in ambulatory cancer patients except in very high risk settings. Another area of increasing research interest is the potential role of anticoagulants on tumor growth, invasiveness and metastasis. Several randomized controlled trials have suggested a potential benefit of anticoagulation on cancer patient survival. Additional investigation into these and related questions should represent a high priority area for future basic and translational cancer research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.149
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.313
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2009
Admission routes1
Has abstractyes

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