Consensus statement for inert gas washout measurement using multiple- and single- breath tests
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
Abstract
Inert gas washout tests, performed using the single- or multiple-breath washout technique, were first described over 60 years ago. As measures of ventilation distribution inhomogeneity, they offer complementary information to standard lung function tests, such as spirometry, as well as improved feasibility across wider age ranges and improved sensitivity in the detection of early lung damage. These benefits have led to a resurgence of interest in these techniques from manufacturers, clinicians and researchers, yet detailed guidelines for washout equipment specifications, test performance and analysis are lacking. This manuscript provides recommendations about these aspects, applicable to both the paediatric and adult testing environment, whilst outlining the important principles that are essential for the reader to understand. These recommendations are evidence based, where possible, but in many places represent expert opinion from a working group with a large collective experience in the techniques discussed. Finally, the important issues that remain unanswered are highlighted. By addressing these important issues and directing future research, the hope is to facilitate the incorporation of these promising tests into routine clinical practice.
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The record
- Venue
- European Respiratory Journal
- Topic
- Respiratory Support and Mechanisms
- Field
- Medicine
- Canadian institutions
- —
- Funders
- Hospital for Sick ChildrenGreat Ormond Street Hospital for ChildrenInselspital, Universitätsspital BernMurdoch Children's Research InstituteChildren’s Hospital of Wisconsin Research InstituteSahlgrenska AkademinUniversity of BernGöteborgs UniversitetEuropean Respiratory SocietyNational Institute for Health and Care ResearchAmerican Thoracic Society
- Keywords
- MedicineSpirometryLung functionWashoutIntensive care medicineMedical physicsTest (biology)Clinical PracticeRisk analysis (engineering)LungFamily medicineInternal medicine
- Has abstract in OpenAlex
- yes