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Record W2137759062 · doi:10.1007/978-1-60327-289-6

Probiotics in Pediatric Medicine

2009· book· en· W2137759062 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueHumana Press eBooks · 2009
Typebook
Languageen
FieldHealth Professions
TopicInfant Health and Development
Canadian institutionsnot available
FundersCanadian Institutes of Health ResearchHospital for Sick ChildrenCrohn's and Colitis Foundation of CanadaNorth American Society for Pediatric Gastroenterology, Hepatology and NutritionCanadian Association of GastroenterologyCrohn's and Colitis Foundation
KeywordsMedicine

Abstract

fetched live from OpenAlex

TABLE OF CONTENTS / ORGANIZATION I Introductory Chapters 1. Basics of GI Physiology and Mucosal Immunology (A Fasano) This introductory chapter will provide an overview of the gastrointestinal physiology and mucosal immunity as it relates to the gut with its microflora and its role in the overall health of the child. 2. Basics of Gut Microflora (G Tannock) This chapter will cover the significance of microflora and the traditional and molecular advances in identifying gut microflora. 3. Role of Microflora in Disease (M. Relman). The focus of this chapter is to review the role of microflora in gastrointestinal disorders with a focus on inflammatory bowel disease and irritable bowel syndrome. A review of the role of microflora in non-gastrointestinal disease such as atopic disorders will be included. 4. Probiotics 101 (WA Walker). This chapter will provide the history of probiotic use and the basics for probiotic concepts as it relates to children. 5. Mechanism of Action of Probiotics (B Polk). This chapter will review the basic research pertaining to the mechanism of action of probiotics as evidence by cellular/molecular studies as well as animal studies. 6. Safety of Probiotics (D Mack). The safety of the different types and forms of probiotics will be reviewed with a focus on children. Michail, Probiotics-p. 4 II Infant Health and Probiotics 7. Neonatal and Infant Microflora (JI Gordon) This chapter will identify the development of microflora in the newborn infant and the factors that affect the composition of microflora such as breast feeding versus formula feeding, age of infant and child, mode of child delivery etc... 8. Probiotics in Infant Dietetics (Agostoni). This chapter will review the evidence, or lack thereof,to support the benefit of adding probiotics to infant formulas or infant foods. 9. Probiotics and Nectrotizing Enterocolits (Zvi Weizman). The focus of this chapter will be the role of probiotics and prevention or treatment of necrotizing enterocolitis. III Pediatric GI and Related Diseases - Is There a Role for Probiotics? 10. Irritable Bowel Disease (S Michail). A review of the literature with regards to irritable bowel syndrome will be presented in this chapter. Pediatric data will be reviewed. 11. Infectious Diarrhea (G Fuchs) The role of probiotics in treating and preventing infectious diarrhea in pediatric patients will be covered in this chapter. 12. Crohn's Disease (A Bousvaros) The role of probiotics in treatment and prevention of relapse of Crohn's disease will be reviewed in this chapter. Pediatric data will be discussed as well. 13. Ulcerative Colitis (PM Fedorak) The role of probiotics in treatment and prevention of relapse of ulcerative colitis will be reviewed in this chapter. Any pediatric data will be reviewed. 14. Pouchitis (P Gionchetti) The role of probiotics in prevention and treatment of pouchits will be reviewed in this chapter. Pediatric data will be discussed as well. 15. Antibiotic-associated Diarrhea and Clostridium difficile Infection (H Szajewska). The role of probiotics and treatment and prevention of these disorders with review of the evidence and meta-analysis will be discussed in this chapter. 16. Probiotics in the Immune-compromised Host (T Poussa). This chapter will review the published studies related to the use of probiotics in various disorders affecting the host immune response and immunocompromised states. Michail, Probiotics-p. 5 17. H. Pylori Infection (PM

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.074
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.148
GPT teacher head0.421
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it