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Transmissible Extragenital Venereal Tumor in Impuberal Canine

2013· article· en· W2137983240 on OpenAlexaboutno aff
Yasmin Duarte Mateus Varela, Genílson Fernandes de Queirõz, Kilder Dantas Filgueira, Paulo Fernando Cisneiros da Costa Reis, Reynaldo Lima

Bibliographic record

VenueBrazilian Journal of Veterinary Pathology · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVirus-based gene therapy research
Canadian institutionsnot available
Fundersnot available
KeywordsLesionPuppyMedicineSex organExternal genitaliaVinblastineVincristinePathologyChemotherapySurgeryCyclophosphamideBiologyAnatomy

Abstract

fetched live from OpenAlex

Transmissible venereal tumor (TVT) is commonly observed in the external reproductive organs of sexually active canines. However, this tumor can unusually be identified in young dogs which have not reached reproductive capacity. In these latter animals, the tumor presentation is located in regions distant from the genitalia as integument and mucous membranes of body cavities. This study aimed to describe a case of TVT in a puppy dog. A seven month old female dog of the Labrador breed, had disseminated nodules in the skin and left conjunctival mucosa. Cytological examination of the proliferation was chosen, which led to the diagnosis of TVT. Since the dog showed no genital lesions, as she was impuberal, this was considered as an extragenital case. Chemotherapy protocol was established with vincristine sulfate, with complete remission of the lesion at the end of the fourth session. Later there was recurrence of the cutaneous TVT, being employed salvage therapy with vinblastine. However there was tumor resistance to such a drug. Surgical excision of the recurrent lesion was performed. It was demonstrated that TVT may also be adapted to other tissues and affect not only dogs at reproductive age, but also those at the pre-pubertal age.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.300
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueBrazilian Journal of Veterinary PathologySame topicVirus-based gene therapy researchFrench-language works237,207