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Record W2138654288 · doi:10.1136/ebm.7.1.4

"Double blind, you are the weakest link -- goodbye!"

2002· editorial· en· W2138654288 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEvidence-Based Medicine · 2002
Typeeditorial
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcMaster University
Fundersnot available
KeywordsBlindingDouble blindMasking (illustration)MedicineRandomized controlled trialPsychologyAlternative medicinePlaceboPathology

Abstract

fetched live from OpenAlex

Double blind is the term researchers frequently use, and readers frequently accept, as a key marker of validity of a randomised controlled trial (RCT). Clinical trial experts and clinicians, when asked, all claim to “know” what double blind means; however, unfortunately it means diverse things to those questioned.1 The term lacks consistency in its use and interpretation — a critical flaw for any technical term if it is to be understood. In this editorial, we advocate abandoning the current blinding lexicon (ie, single, double, and triple blinding) and recommend transparent reporting of the blinding status of each group involved in the execution, monitoring, and reporting of clinical trials. Blinding (or masking) in RCTs is the process of withholding information about treatment allocation from those who could potentially be influenced by this information. Blinding has long been considered an important safeguard against bias. Benjamin Franklin, in 1784, was probably the first to use blinding in scientific experimentation.2 Louis …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearch
Domain: Methods · Genre: Editorial
About the Canadian research system: no · About a Canadian topic: no
Not applicablelow
gptMetaresearch
Domain: Methods · Genre: Editorial
About the Canadian research system: no · About a Canadian topic: no
Not applicablelow
models agreeAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.229
metaresearch head score (Gemma)0.419
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Scholarly communication, Open science, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch, Meta-epidemiology (narrow), Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.190
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.2290.419
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0110.004
Bibliometrics0.0010.004
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0100.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0490.019

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.778
GPT teacher head0.531
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it