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Record W2139842191 · doi:10.1177/0300985810377187

Recommended Guidelines for the Conduct and Evaluation of Prognostic Studies in Veterinary Oncology

2010· article· en· W2139842191 on OpenAlexaff
Joshua D. Webster, Michelle M. Dennis, Nikolaos Dervisis, Jane Heller, Nicholas J. Bacon, Philip J. Bergman, Dorothee Bienzle, Geovanni Dantas Cassali, Massimo Castagnaro, John M. Cullen, D. Glen Esplin, L. Peña, Michael H. Goldschmidt, K. Hahn, Carolyn J. Henry, Eva Hellmén, Debra A. Kamstock, Jolle Kirpensteijn, Barbara E. Kitchell, Renée Laufer Amorim, Stephen D. Lenz, Thomas P. Lipscomb, Michael F. McEntee, Lawrence D. McGill, Courtney McKnight, Patricia M. McManus, Antony S. Moore, Peter F. Moore, Scott Moroff, Hiroyuki Nakayama, Nicole C. Northrup, Giuseppe Sarli, T. Scase, Karin U. Sørenmo, F. Y. Schulman, Ahmed Shoieb, Rebecca C. Smedley, W. L. Spangler, Erik Teske, Douglas H. Thamm, V. E. Valli, William Vernau, Henrik von Euler, Stephen J. Withrow, Steven E. Weisbrode, Julie A. Yager, Matti Kiupel

Bibliographic record

VenueVeterinary Pathology · 2010
Typearticle
Languageen
FieldMedicine
TopicVeterinary Oncology Research
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsMedicineInternal medicineOncologyStandardizationVeterinary medicineVeterinary pathologyPathology

Abstract

fetched live from OpenAlex

There is an increasing need for more accurate prognostic and predictive markers in veterinary oncology because of an increasing number of treatment options, the increased financial costs associated with treatment, and the emotional stress experienced by owners in association with the disease and its treatment. Numerous studies have evaluated potential prognostic and predictive markers for veterinary neoplastic diseases, but there are no established guidelines or standards for the conduct and reporting of prognostic studies in veterinary medicine. This lack of standardization has made the evaluation and comparison of studies difficult. Most important, translating these results to clinical applications is problematic. To address this issue, the American College of Veterinary Pathologists' Oncology Committee organized an initiative to establish guidelines for the conduct and reporting of prognostic studies in veterinary oncology. The goal of this initiative is to increase the quality and standardization of veterinary prognostic studies to facilitate independent evaluation, validation, comparison, and implementation of study results. This article represents a consensus statement on the conduct and reporting of prognostic studies in veterinary oncology from veterinary pathologists and oncologists from around the world. These guidelines should be considered a recommendation based on the current state of knowledge in the field, and they will need to be continually reevaluated and revised as the field of veterinary oncology continues to progress. As mentioned, these guidelines were developed through an initiative of the American College of Veterinary Pathologists' Oncology Committee, and they have been reviewed and endorsed by the World Small Animal Veterinary Association.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.170
metaresearch head score (Gemma)0.383
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.830
Threshold uncertainty score0.899

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1700.383
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0050.008
Bibliometrics0.0150.016
Science and technology studies0.0040.006
Scholarly communication0.0070.005
Open science0.0130.004
Research integrity0.0200.021
Insufficient payload (model declined to judge)0.0130.013

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.695
GPT teacher head0.600
Teacher spread0.095 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations94
Published2010
Admission routes1
Has abstractyes

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