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Record W2139889312 · doi:10.1002/9781118921692.ch6

Neuroendocrine Mechanisms of Stress Regulation in Humans

2015· other· en· W2139889312 on OpenAlexaff
Jens C. Pruessner, Nida Ali

Bibliographic record

Venuenot available
Typeother
Languageen
FieldNeuroscience
TopicStress Responses and Cortisol
Canadian institutionsMcGill University
Fundersnot available
KeywordsFight-or-flight responseNeuroscienceStress (linguistics)Function (biology)Cognitive scienceComputer sciencePsychologyBiologyEvolutionary biology

Abstract

fetched live from OpenAlex

Stress research has made profound discoveries over the past few years. In line with the notion that the acute stress response aims at re-establishing an equilibrium that was disturbed by the stressful agent, the various stress systems in the human body interact, being directed by specific brain structures and systems. The interplay between these systems regulating the stress response in the human are complex and we are only beginning to understand their interaction and their net effect on the regulation of the stress response. Various brain systems are either inhibitory or excitatory to the activation of the stress systems and can change their role depending on the amount of circulating glucocorticoids and the status of the perceived threat. New assessment and manipulation methods now allow a better understanding of the function of these various systems, and their interaction, when it comes to the processing of stress in humans. In this chapter, some of the basics of these systems and structures are first reviewed before discussing some recent developments, which the authors believe have the possibility to allow for refined experimental stress designs in the future.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.289
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2015
Admission routes1
Has abstractyes

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