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Record W2139970241 · doi:10.1186/1753-6561-7-s2-p21

The role of Met, Src and Stat3 in basal-like breast cancer invasion

2013· article· en· W2139970241 on OpenAlexaff
Esther Carefoot, L Raptis, P.A. Greer, B E Elliott

Bibliographic record

VenueBMC Proceedings · 2013
Typearticle
Languageen
FieldMedicine
TopicLiver physiology and pathology
Canadian institutionsQueen's University
Fundersnot available
KeywordsBasal (medicine)MedicineBreast cancerSTAT3Proto-oncogene tyrosine-protein kinase SrcKinaseOncologyCancerInternal medicineCancer researchDiseasePathologyPhosphorylationBiologyReceptorCell biology

Abstract

fetched live from OpenAlex

Background The basal-like subtype of human breast cancers has no clinically defined marker profile. Recent studies have shown that Met as well as certain Src family kinases are over-expressed in basal-like breast cancers and correlate with disease progression and poor prognosis. Our group has also demonstrated a potential regulatory role of Stat3 on Met activation or turnover, adding to the previously identified roles of Stat3.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.128
Threshold uncertainty score0.174

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.240
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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