Microfabricated electrolysis pump system for isolating rare cells in blood
Bibliographic record
Abstract
An integrated system for immunomagnetic separation of rare cells from blood is presented. A micromachined device was fabricated by bonding silicon die with etched structures to a glass cover plate on which electrodes are defined. Electrolytic generation of gas from 0.50 M KNO3 (aqueous) provided pumping actuation for a device that performed the capture and purification of rare cells spiked into a 7.5 ul reconstituted blood sample. The system consisted of two pumps, a sample and a wash buffer meander reservoir, and a main channel for magnetic field trapping of rare cells captured by antibody-coated magnetic beads. A maximum pumping rate of 1.4 +- 0.1 ul min[?]1 was obtained at a current of 180 uA, and the maximum blood sample volume delivered to the capture bed was 6.5-7 ul. The trapped cells could be washed with the buffer from the second pump and then delivered to the exit port of the chip after removing the magnetic field.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".