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Record W2141394615 · doi:10.1002/mrm.22279

Steering of aggregating magnetic microparticles using propulsion gradients coils in an MRI Scanner

2010· article· en· W2141394615 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueMagnetic Resonance in Medicine · 2010
Typearticle
Languageen
FieldEngineering
TopicCharacterization and Applications of Magnetic Nanoparticles
Canadian institutionsPolytechnique Montréal
Fundersnot available
KeywordsMaterials scienceScannerMagnetic nanoparticlesPerpendicularElectromagnetic coilAmplitudeMicrofluidicsSuspension (topology)Nuclear magnetic resonanceMagnetic fieldSpectroscopyAnalytical Chemistry (journal)MechanicsPhysicsChemistryOpticsNanotechnologyNanoparticleGeometry

Abstract

fetched live from OpenAlex

Upgraded gradient coils can effectively enhance the MRI steering of magnetic microparticles in a branching channel. Applications of this method include MRI targeting of magnetic embolization agents for oncologic therapy. A magnetic suspension of Fe(3)O(4) magnetic particles was injected inside a y-shaped microfluidic channel. Magnetic gradients of 0, 50, 100, 200, and 400 mT/m were applied to the magnetic particles perpendicularly to the flow by a custom-built gradient coil inside a 1.5-T MRI scanner. Measurement of the steering ratio was performed both by video analyses and quantification of the mass of the particles collected at each outlet of the microfluidic channel, using atomic absorption spectroscopy. Magnetic particles steering ratios of 0.99 and 0.75 were reached with 400 mT/m gradient amplitude and measured by video analyses and atomic absorption spectroscopy, respectively. Experimental data shows that the steering ratio increases with higher magnetic gradients. Moreover, theory suggests that larger particles (or aggregates), higher magnetizations, and lower flows can also be used to improve the steering ratio. The technological limitation of the approach is that an MRI gradient amplitude increase to a few hundred milliteslas per meter is needed. A simple analytical method based on magnetophoretic velocity predictions and geometric considerations is proposed for steering ratio calculation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.744
Threshold uncertainty score0.680

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.255
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it