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Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell–mediated innate resistance to cytomegalovirus infection

2005· article· en· 149 citations· W2143244825 on OpenAlex· 10.1038/ng1564

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Immunogenetics of NK-cell resistance to cytomegalovirus in mice.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

The study concerns immune genetics and cytomegalovirus resistance, not research itself.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Domain immunology genetics of viral resistance, not metaresearch.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Genetics
Topic
Immune Cell Function and Interaction
Field
Immunology and Microbiology
Canadian institutions
Institut National de la Recherche ScientifiqueMontreal Clinical Research InstituteMcGill University
Funders
National Cancer Institute
Keywords
BiologyMajor histocompatibility complexInnate immune systemMechanism (biology)ImmunologyNatural killer cellEpistasisCytomegalovirusGeneticsVirologyImmune systemGeneVirusHerpesviridaeCytotoxic T cellViral diseaseIn vitro
Has abstract in OpenAlex
no