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Record W2144868251 · doi:10.1002/ana.24345

Lipid‐specific immunoglobulin <scp>M</scp> bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

2015· article· en· W2144868251 on OpenAlex
Luisa María Villar, Lucienne Costa‐Frossard, Thomas Masterman, Óscar Fernández, Xavier Montalbán, Bonaventura Casanova, Guillermo Izquierdo, Francisco Coret, Hayrettin Tumani, Albert Saiz, Rafael Arroyo, Katharina Fink, Laura Leyva, Carmen Espejo, María Simó, Maria-Isabel García-Sanchéz, Florian Lauda, Sara Llufriú, Roberto Álvarez‐Lafuente, Javier Olascoaga, Álvaro Prada, Agustı́n Oterino, Clara de Andrés, Mar Tintoré, Lluís Ramió‐Torrentà, Eulalia Rodríguez‐Martín, Carmen Picón, Manuel Comabella, Ester Quintana, Eduardo Agüera, Santiago Díaz, Ricardo Fernández‐Bolaños, Juan A. García‐Merino, Lamberto Landete, Manuel Menéndez‐González, Laura Navarro-Cantó, D. Robles Pérez, Fernando Sánchez‐López, Pedro J. Serrano‐Castro, Alberto Hidalgo Tuñón, Mercedes Espiño, Alfonso Muriel, Amit Bar‐Or, José C. Álvarez‐Cermeño

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAnnals of Neurology · 2015
Typearticle
Languageen
FieldMedicine
TopicPolyomavirus and related diseases
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
Fundersnot available
KeywordsNatalizumabProgressive multifocal leukoencephalopathyMultiple sclerosisCerebrospinal fluidMedicineOdds ratioAntibodyGastroenterologyInternal medicineImmunologyOpportunistic infectionJC virusConfidence intervalViral diseaseVirus

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.819

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.290
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it