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Record W2145381776 · doi:10.1016/j.crvi.2010.12.005

Les nucléosides et nucléotides extracellulaires régulent les fonctions hépatiques par le biais d’un système complexe de protéines membranaires

2011· review· fr· W2145381776 on OpenAlexafffund
Michel Fausther, Jean Sévigny

Bibliographic record

VenueComptes Rendus Biologies · 2011
Typereview
Languagefr
FieldBiochemistry, Genetics and Molecular Biology
TopicAdenosine and Purinergic Signaling
Canadian institutionsUniversité LavalCentre hospitalier universitaire de Québec
FundersCanadian Institutes of Health Research
KeywordsMolecular biologyPhysicsBiology

Abstract

fetched live from OpenAlex

Les nucléosides et nucléotides extracellulaires sont maintenant reconnus comme des molécules de signalisation au même titre que les neurotransmetteurs et les hormones. Les cellules hépatiques, comme la majorité des autres cellules de l’organisme, expriment plusieurs récepteurs transmembranaires spécifiques ainsi que plusieurs ectoenzymes dont ces médiateurs sont les ligands et les substrats, respectivement. Cette revue de littérature présente l’état des connaissances actuelles sur la signalisation par les nucléosides et nucléotides extracellulaires dans le foie (en y incluant les sources, la transduction de signal et le métabolisme), ainsi que sur leur contribution dans le maintien de l’homéostasie cellulaire hépatique.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.082
GPT teacher head0.311
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2011
Admission routes2
Has abstractyes

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