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Record W2145385227 · doi:10.1126/science.1060966

The Composite Genome of the Legume Symbiont <i>Sinorhizobium meliloti</i>

2001· article· en· W2145385227 on OpenAlexaff
Francis Galibert, Turlough M. Finan, Sharon R. Long, Alfred Pühler, Pia Abola, Frédéric Ampe, Frédérique Barloy-Hubler, Melanie J. Barnett, Anke Becker, P. Boistard, Gordana Bothe, Marc Boutry, Leah Bowser, Jens Buhrmester, Édouard Cadieu, Delphine Capela, Patrick Chain, Alison Cowie, Ronald W. Davis, Stéphane Dréano, Nancy A. Federspiel, Robert F. Fisher, Stéphanie Gloux, Thérèse Godrie, André Goffeau, Brian Golding, Jérôme Gouzy, Mani Gurjal, Ismael Hernández-Lucas, Andrea Hong, Lucas Huizar, Richard W. Hyman, Ted Jones, Daniel Kahn, Michael L. Kahn, Sue Kalman, David H. Keating, Ernö Kiss, C. Komp, Valérie Lelaure, David Masuy, Curtis Palm, Melicent C. Peck, Thomas Pohl, Daniel Portetelle, Bénédicte Purnelle, U. Ramsperger, Raymond Surzycki, Patricia Thébault, Micheline Vandenbol, Frank-J. Vorhölter, Stefan Weidner, Derek H. Wells, Kim Wong, Kuo‐Chen Yeh, Jacques Batut

Bibliographic record

VenueScience · 2001
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicLegume Nitrogen Fixing Symbiosis
Canadian institutionsMcMaster University
FundersNational Institute of General Medical Sciences
KeywordsSinorhizobium melilotiBiologyGenomeWhole genome sequencingNitrogen fixationSymbiosisBacteriaCircular bacterial chromosomeGeneticsGene

Abstract

fetched live from OpenAlex

The scarcity of usable nitrogen frequently limits plant growth. A tight metabolic association with rhizobial bacteria allows legumes to obtain nitrogen compounds by bacterial reduction of dinitrogen (N2) to ammonium (NH4+). We present here the annotated DNA sequence of the alpha-proteobacterium Sinorhizobium meliloti, the symbiont of alfalfa. The tripartite 6.7-megabase (Mb) genome comprises a 3.65-Mb chromosome, and 1.35-Mb pSymA and 1.68-Mb pSymB megaplasmids. Genome sequence analysis indicates that all three elements contribute, in varying degrees, to symbiosis and reveals how this genome may have emerged during evolution. The genome sequence will be useful in understanding the dynamics of interkingdom associations and of life in soil environments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.199
Teacher spread0.189 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1,159
Published2001
Admission routes1
Has abstractyes

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