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Record W2145421468 · doi:10.5897/bmbr2009.0002

The development of the pitcher plant Sarracenia purpurea into a potentially valuable recombinant protein production system

2009· article· en· W2145421468 on OpenAlexaff
Bruce A. Rosa, Lada Malek, Wensheng Qin

Bibliographic record

VenueBiotechnology and Molecular Biology Reviews · 2009
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant and Biological Electrophysiology Studies
Canadian institutionsLakehead University
Fundersnot available
KeywordsRecombinant DNABiologyGenetically modified cropsTransgeneBotanyBiotechnologyGeneBiochemistry

Abstract

fetched live from OpenAlex

The unique inducible system of protein secretion by the carnivorous pitcher plantSarracenia purpurea may be an ideal system for recombinant protein farming. S. purpurea is relatively uncommon and difficult to grow in vitro, so it has not been explored as a potential source of recombinant proteins. However, it naturally secretes large amounts of proteins into a liquid found in the leaf pitchers, so it may be an ideal way to collect recombinant proteins in leaf pitchers. Here, the advantages of transgenic S. purpurea systems over traditional transgenic plant systems for the production of recombinant pharmaceutical proteins are explored, and the steps necessary to produce such a system are discussed.   Key words: Transgenic plants, recombinant protein farming, carnivorous plants, gene technology

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.271
Threshold uncertainty score0.551

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.218
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2009
Admission routes1
Has abstractyes

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